I have purchased several times from this specific seller on amazon and have noticed significant variability in the products effects based on different bottles i have received. I was using a bottle i purchased a month or two ago and noticed that the magnesium L-threonates effects I was used to feeling (memory/sleep/focus) were no longer there, I attributed this to maybe building a tolerance but noticed that when i ordered a new bottle recently, the pills from it it felt how i was used to feel from Magnesium L-threonate with all of its benefits (memory/sleep/focus). I had a few pills left from the old bottle and took them again to test my theory and i felt horrible (lightheaded/dizzy) again from the old pills again! I don't know if some bottle contain normal magnesium (Not Mg L-threonate) or if they contain something else (which is very scary to think about). Take my review as you may, but something unusual is going on.

I love Magnesium, I've been taking it for years. I started out with Natural Calm which sometimes hurt my stomach, so I switched to Magnesium Glycinate which worked amazingly (for me) for relaxation and sleep.<br /><br />I was excited to try Magnesium L-Threonate after reading about its ability to cross the blood-brain barrier and support cognitive function and memory.<br /><br />When I try a supplement out for the first time, I always use less than the recommended dose &#34;just in case&#34;.<br /><br />I took 2 MagMind pills before bed and 30 minutes later as I was falling asleep, my mind started RACING. I became very anxious and agitated.<br /><br />Thankfully that feeling passed, but it was extremely unpleasant.<br /><br />The next day I had a headache all day, along with blurry vision. I am not someone who is prone to headaches. (Unless I've had too much wine.)<br /><br />I tried the MagMind one more time, dropping down to 1 pill before bed. Same result, slightly less dramatic.<br /><br />Unfortunately, this form of Magnesium does not agree with me and I will not be able to keep using it.

Jarrow Formulas MagMind is probably the best overall Magnesium L-Threonate supplement available, and like most supplements there are all sorts of claims about what this can do. I've not seen good evidence to support this besides the fact most people tend to be short their RDA for any magnesium, and this didn't really move my labs much so I can't say with any certainty that it did anything. Still, compared to a lot of the more marginal brands on the market, if you're going to experiment with Magtein, this is probably what you should be doing it with. 4 stars.

I have been using Jarrow Formula supplements for a number of years, especially the Vitamin B12 - methylcobalamin and Vitamin K2 - MK7 supplements. I have been impressed with their continuing development of new *effective* products at a great price point.<br /><br />My husband and I have been taking approximately a gram a day of supplement Magnesium (cheaper products) for almost 5 years now. In that time we have cured his former type 2 diabetes (after almost a 2 decade battle with medicated fasting BGs in the 500s at one point!) and we have almost completely reversed his hypertension of many years as well has have turned his end stage Severe Congestive Heart Failure around so he's relatively free of symptoms. I credit not only the magnesium, but also high doses of Vitamin D (ALWAYS taken with magnesium and fish oil!!), a whole foods source multi, the Sinatra Protocols for supplements as found in the back of [[ASIN:1591202914 The Sinatra Solution: Metabolic Cardiology]] and a number of minerals especially trace minerals as found in [[ASIN:B000AMUWLK Liqumins ConcenTrace Trace Mineral Drops, Low Sodium, 8-Ounce Bottle]].<br /><br />I was looking into research on magnesium and the brain when I ran into the MIT study published in 2010 showing magnesium L-threonate is the only form of magnesium to cross the blood-brain barrier and showed observable improvements in cognitive measures. Interesting. So we bought a bottle at our local neighborhood nutrition shop after a discussion with the owner, a couple I have come to trust during our many battles with the medical establishment.<br /><br />Jarrow Formulas of magnesium L-threonate as Magmind is a very cost-effective source. To further economize we are still taking our regular magnesium supplement 3 times a day (750 mg) then taking this form of magnesium as part of our bed time routine (replacing the 4th magnesium of the day). I am genuinely impressed. Our sleep has improved yet another notch, which is saying something since the 5 years of magnesium supplementation meant we already had really good sleep quality. What I have noticed is that after multiple head trauma injuries (including a serious concussion earlier this year) my previously very high level of spatial relations was slipping. Now with Jarrow I feel I'm getting that edge back. I am very impressed. I will update again with further results after we've been taking this formula longer.<br /><br />2015 UPDATE - in the years since we first tried MagMind I've referred hundreds of people to try this quality supplement with great results. We've since learned to couple magnesium with taurine for even greater results. Taurine is VERY well documented to improve the fluidity of electrolytes within the cells including within the brain.<br /><br />NOVEMBER 2016 UPDATE:<br />Well, here we are 4 years later. We still personally use and recommend MagMind. What we discovered though, since he was put on Armour Thyroid by our primary care he no longer seems to be &#34;leaking&#34; magnesium hence we've cut magnesium supplementation waaayy back. Plus we soak in epsom salts far more. Magnesium is still vital however we're no longer &#34;taking a gram a day.&#34;

This is a great product. My 10 year old son has ADHD and when he started these supplements we definitely saw positive changes in his behavior and schoolwork.

This is my experience for my body chemistry. I am not a physician and have no medical training. With those caveats I am willing to say that i believe I have experienced greater mental sharpness because of this supplement. Two times I have been in a situation where I did not take the supplement for a week or two and when I restarted taking it I noticed an almost immediate increase in mental sharpness. The initial improvement did not seem to kick in until I had been taking it for about four months. I also take high absorption chelated magnesium (also a brain oriented supplement) so I am unable to tell you if the effect was due to the combination. I use 1 pill of high absorption chelated magnesium to replace one of the the recommended three daily pills of the magtein. I may be totally imagining the effect but in my opinion it has boosted my memory and cognition noticeably.<br /><br />I have noticed three side effects that seem relatively minor in light of the significant cognitive improvements. First, I seem to be awake more fully when I wake up at night, making it more difficult to go back to sleep. Second, I do seem to have to get up more often at night to urinate - about 3 more times. Thirdly, I seem to have a minor headache in the morning about 4 days a week but I am never groggy anymore when I wake up.<br /><br />UPDATE 7/30/18<br /><br />A side benefit i have noticed is that when i hear a noise in the house i wake up immediately and am fully alert, no grogginess, but it is still difficult to convince myself to get out of bed.<br /><br />Update 12/30/19<br />The need for frequent night urination has subsided, unless I drink a lot of liquid in the evening.<br /><br />I never rate a product as 5 stars unless it is superb or unique.