IMPORTANT DOSING INFO
Through some research I've discovered some important things about when and how to take Leucine.<br /><br />Do not's:<br /><br />1) Do not take before your workout. Leucine stimulates the production of glycogen from glucose, and simultaneously prevents glycogen's breakdown into glucose, so you won't be getting enough energy to your muscles during your workout.<br /><br />2) Do not take leucine without food or in a fasted state. if you want to prevent catabolism, or muscle breakdown, take HMB. Leucine should be reserved for times you want to promote muscle synthesis, or anabolism.<br /><br />3) Do not take leucine consistently throughout the day. Leucine can cause insulin resistance when taken in large amounts and too consistently.<br /><br />4) Do not take in the morning. This is not an optimum time to build muscle anyway, as your body's natural cortisol spike is then. Wait until afternoon/evening.<br /><br />Do's:<br /><br />1) Take leucine with meals. Leucine signals muscle synthesis, so making sure you have the protein, carbohydrates and nutrients to go along with that is key. Taking leucine with a meal ensures you'll get a useful spike in insulin, and the body can get straight to building muscle.<br /><br />2) Take leucine intermittently in spikes. Choose a large meal toward the end of the day to take your leucine so you're body will have a lot to build muscle with and can build it while cortisol is low in the evening and while sleeping. On days you workout, taking it with a meal after you workout and a meal in the evening can still make sense. Avoid taking it during every meal during the day to prevent insulin resistance.<br /><br />So, a proper dosing schedule would be a tablespoon with dinner, and on days you have an especially heavy workout, a tablespoon with a meal after working out and another teaspoon with an evening meal before bed.





